Concomitant use with carbamazepine may cause an increase in Ondansetron clearance resulted in decreasing Ondansetron blood level.
Concomitant use with phenytoin may cause an increase in Ondansetron clearance resulted in decreasing Ondansetron blood level.
Concomitant use with rifamycins may cause a decrease in Ondansetron plasma concentration.
Concomitant use with cisplatin may cause a decrease in cisplatin plasma concentration which may reduce its therapeutic effect. Therefore, it may be necessary to increase cisplatin dose when used in combination.
Concomitant use with cyclophosphamide may cause a decrease in cyclophosphamide plasma concentration which may reduce its therapeutic effect. Therefore, it may be necessary to increase cyclophosphamide dose when used in combination.
Concomitant use with apomorphine may enhance hypotensive effect of apomorphine. Concurrent use is contraindicated.
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