Omeprazole has the potential to interfere with the Cytochrome P450 enzyme system and then to induce or inhibit the metabolism of drugs like diazepam, warfarin and phenytoin. Because of its profound and long lasting inhibition of gastric acid secretion, Omeprazole may interfere with absorption of drugs where gastric pH is an important determination of their bioavailability (eg. Ketoconazole, Ampicillin, Esters and Iron salts).
Sign up for Free to continue reading
Asia's one-stop resource for medical news, clinical reference and education
Sign Out
