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Hypersensitivity to olmesartan medoxomil, hydrochlorothiazide or to any of the excipients of Olmetec Plus (see Description for the list of excipients), or to other sulphonamide-derived substances (since hydrochlorothiazide is a sulphonamide-derived medicinal product).
Severe renal impairment (creatinine clearance <30 mL/min); refractory hypokalaemia; hypercalcaemia; chloestasis and biliary obstructive disorders, anuria.
Second and third trimester of pregnancy and lactation. (See Use in pregnancy and Use in lactation under Precaution.)
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