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Orphenadrine may impair the ability of the patient to engage in potentially hazardous activities such as operating machinery or driving a motor vehicle; ambulatory patient should therefore be cautioned accordingly. Orphenadrine citrates should be used with caution in patients with tachycardia, cardiac decompensation, coronary insufficiency, cardiac arrhythmias. Safety of continuous long-term therapy with orphenadrine has not been established. Therefore, if orphenadrine is prescribed for prolonged use, periodic monitoring of blood, urine and liver function is recommended.
Use in Pregnancy: Safe use in pregnancy has not been established, therefore the drug should not be used in pregnant women or those likely to become pregnant unless the expected benefits outweigh the potential risks.
Use in Lactation: Not applicable.
Use in Children: Not applicable.
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