NIKP-Pitavastatin Dosage/Direction for Use

Recommended Dose: Adult: Initial Dosage: 2 mg once daily.
Maintenance dosage: 1 to 4 mg once daily.
Maximum dose: 4 mg once daily.
Dosage adjustment: After initiation or upon titration of Pitavastatin, lipid levels should be analyzed after 4 weeks and the dosage adjusted accordingly.
Geriatric Use: In clinical studies of pitavastatin, approximately 43% of patients were 65 years of age or older. No substantial differences in safety or efficacy relative to younger adults were observed but increased sensitivity in some older patients can not be ruled out.
The ACC/AHA cholesterol management guidelines states that initiation of statin therapy for primary prevention of ASCVD in patients older than 75 years of age requires consideration of additional factors including increasing comorbidities, safety, considerations, and priorities of care.
Thus, the potential for an ASCVD risk reduction, benefit, adverse effects, and drug interactions, along with patients' preferences, must be considered before initiating statin therapy in patients older than 75 years of age.
Paediatric Use: Safety and efficacy of Pitavastatin have not been established in pediatric patients younger than 18 years old of age.
Dosage adjustment in patients with renal insufficiency and concomitant with other medicines. (See Table 4.)

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Mode of Administration: Pitavastatin is administered orally once daily at any time of day, without regard to food.