Niflec Dosage/Direction for Use

Dissolve 1 pack of Niflec in water to make about 2 L of solution. Orally administer 2-4 L of the dissolved solution at a rate of about 1 L/hr. Discontinue dosing when excretion liquid becomes clear. Refrain from dosing >4 L.
Pre-treatment for Colonoscopy: Administration on the Day of Examination: Refrain from having breakfast on the day of examination (water intake is acceptable) and start dosing from about 4 hrs ahead of the scheduled time of examination.
Administration on the Day Before Examination: Refrain from having any food after previous day's supper (water intake is acceptable) and start dosing after at least 1 hr has elapsed following supper. The previous day's breakfast and lunch must contain smaller amounts of residue and supper must consist of liquid food (contains no solid matter).
Pre-treatment for Large Bowel Operation: Fast after lunch on the day before operation (water intake is acceptable) and start dosing after at least 3 hrs have elapsed following lunch.
Administration: Method of Preparation: Dissolve 1 full bag of Niflec in water to make about 2 L and then administer to subjects (since the individual ingredients in the bag are not mixed homogeneously, be sure to dissolve 1 full bag at a time).
Preparation: No additional ingredients or flavoring should be added to Niflec solution (see Important Basic Precautions under Precautions).
Dosing Velocity: Transfer the dissolved solution (about 180 mL) to glasses to get 6 glassfuls (about 1 L/hr) as a guide.
In most cases, defecation starts more or less from the time about 1 L of the product is administered, and defecation occurs several times thereafter; continue administration (with 4 L as maximum) until the rectal effluent turns clear. Defecation may be produced several times even after the subjects are given 2 L. Discontinue administration and resume when nausea, vomiting and abdominal pain are absent and when defecation is present.
It should be noted that Niflec is not suited for pre-treatment for barium enema x-ray colonography.