Mild to moderate HTN Initially 20 mg once daily, may be increased up to max of 90 mg once daily. Prophylaxis of angina pectoris Initially 30 mg once daily, may be increased up to max of 90 mg once daily.
May be taken with or without food: Take at the same time each day, preferably in the morning. Swallow whole, do not chew/crush. Avoid grapefruit juice.
Contraindications
Hypersensitivity. Cardiogenic shock, clinically significant aortic stenosis, unstable angina, or MI. Patients w/ history of GI & oesophageal obstruction; Kock pouch; inflammatory bowel disease or Crohn's disease. Concomitant use w/ rifampicin.
Patient w/ hypotension; poor cardiac reserve. Diabetic patient. Dialysis patients w/ malignant HTN & hypovolaemia. May affect ability to drive & use machines. Impaired liver function. Not to be used during pregnancy. Not recommended during lactation.
C08CA05 - nifedipine ; Belongs to the class of dihydropyridine derivative selective calcium-channel blockers with mainly vascular effects. Used in the treatment of cardiovascular diseases.
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