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Careful administration in the following patients: Patients with a history of peptic or active ulcer: Since Merislon has a histamine-like action, it may enhance gastric acid secretion through the intervention of H2-receptors.
Patients with bronchial asthma: Since Merislon has a histamine-like action, it may cause respiratory tract contraction through the intervention of H1-receptors.
Patients with pheochromocytoma: Since Merislon has a histamine-like action, it may cause an increase in blood pressure due to adrenaline hypersecretion.
Effects on Ability to Drive and Operate Machines: Based on the pharmacodynamic properties and the adverse events profile, it is unlikely that Merislon would cause an impairment of driving performance or compromise the ability to use machinery.
Use in Children: The safety in children has not been established (insufficient clinical experience).
Use in Elderly: Since the elderly often have a physiological hypofunction, it is advisable to take measures such as reduction in dosage under careful supervision.
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