Melodia Drug Interactions

Some medicines may stop the Pill from working properly. These include medicines used for the treatment of epilepsy (e.g. primidone, phenytoin, barbiturates, carbamazepine, oxcarbazepine, topiramate, felbamate); tuberculosis (e.g. rifampicin, rifabutin) and HIV infections (e.g. ritonavir, nevirapine); antibiotics (e.g. penicillins, tetracyclines, griseofulvin) for some other infectious diseases; and the herbal remedy St. John's wort (primarily used for the treatment of depressive moods). Some medicines (e.g. ketoconazole, erythromycin, cyclosporine) may inhibit the metabolism of Melodia.
The Pill may also interfere with the working of other medicines. Accordingly, plasma and tissue concentrations may either increase (e.g. cyclosporine) or decrease (e.g. lamotrigine).
There is a theoretical potential for an increase in serum potassium if the patient is taking Melodia with other drugs that may increase serum potassium levels. Such drugs include angiotensin-II-receptor antagonists, diuretics that may increase the potassium in the blood, and aldosterone antagonists. However in studies in women taking drospirenone (combined with estradiol) together with an ACE inhibitor or indomethacin no significant difference in the potassium blood level could be observed.
Inform the doctor or pharmacist if taking or have recently taken any other medicines or herbal products, even those not prescribed. Also tell any other doctor or dentist who prescribes another medicine (or the dispensing pharmacist) that the patient uses Melodia. They can tell if the patient needs to take additional contraceptive precautions and if so, for how long.
Certain laboratory tests may be affected by oral contraceptives.