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Before the treatment, the patient should be place on a standard cholesterol-lowing diet before receiving simvastatin and should continue on this diet during treatment with simvastatin.
Hyperlipidemia: The usual starting dose is 10-20 mg/day given as a single dose in the evening. The recommended dosing range is 5-80 mg/day as a single dose in the evening. Adjustments of dosage should be made at intervals of not less than 4 weeks.
Coronary heart disease: The usual starting dose is 10-20 mg/day given as a single dose in the evening. The maximum dose is 80 mg/day as a single dose in the evening. Adjustments of dosage should be made at intervals of not less than 4 weeks.
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