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This drug should be given with caution to the following patients: Patients with immunoglobulin A deficiency: (Hypersensitivity may be observed in patients with anti-IgA antibody).
Patients with renal disorder: (There is a risk that this drug may aggravate renal function).
Patients with hemolytic or hemorrhagic anemia: (There is a possibility of human parvovirus B19 infection. In case of infection, acute systemic response may occur along with fever and sudden and severe anemia.).
Patients with immunodeficiency or immunodepression: (There is a possibility of human parvovirus B19 infection. In case of infection, prolonged anemia may occur).
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