Lipitor Warnings

Based on Thai Ministry of Public Health Announcement: Do not use the drug in pregnant and breast-feeding women.
Do not use the drug in patients with liver disease.
If there is myalgia at calf, back or whole body, stop taking drug and consult a physician.
Liver function tests should be performed before taking drug and 6 and 12 weeks after taking drug. For patients who routinely use the drug, liver function tests should be performed every 6 months or as recommended by a physician. If the transaminase level is greater than three times of upper normal limit, stop taking drug and consult a physician.
Use with caution with digoxin, warfarin because the level of these drugs in blood may be high and become dangerous.
The risk of myopathy or rhabdomyolysis will increase when the drug is administered with other following drugs, e.g., azole antifungals such as ketoconazole, itraconazole; macrolides such as erythromycin, clarithromycin; HIV protease inhibitors such as indinavir, ritonavir, nelfinavir, saquinavir; verapamil; diltiazem; gemfibrozil; nicotinic acid; cyclosporine; amiodarone.
The risk of rhabdomyolysis will increase under the following conditions, e.g., use at high dose, in the elderly; in patients with hepatic or renal insufficiency; in alcoholism; in patients with hypothyroidism.
Caution should be exercised when taking this drug with colchicine, especially in the elderly, or patients with renal insufficiency because there is a risk of myopathy or rhabdomyolysis.
The use of this drug may increase the risk of increase in blood sugar level.