Lipiodol Ultra-Fluide Drug Interactions

Interactions with other medicines: Metformin: In diabetic patients, intra-arterial administration LIPIODOL ULTRA-FLUIDE may cause lacitc acidosis induced by diminished renal function. In patients undergoing embolization or a Trans-Arterial Chemo-Embolisation, metformin must be discontinued 48 hours before the procedure and resumed no earlier than two days after the procedure.
Combination requiring caution: Beta-blockers, vasoactive substances, angiotensin-converting enzyme inhibitors, angiotensin receptor antagonists: These medicinal products reduce the efficacy of cardiovascular compensation mechanisms for blood pressure disorders. The physician must be aware of this before administering LIPIODOL ULTRA-FLUIDE and emergency measures must be available.
Diuretics: As diuretics may cause dehydration, the risk of acute renal failure is increased, particularly when high doses of contrast agents are administered.
Precautions for use: Rehydration before intra-arterial administration of LIPIODOL ULTRA-FLUIDE for embolisation.
Interleukin 2: Reactions to contrast agents may be increased if the patients has recently been treated with interleukin 2 (i.v.), i.e. skin eruptions or more rarely hypotension, oliguria, or renal failure.
Interference with laboratory results: As LIPIODOL ULTRA-FLUIDE remain in the body for several months, thyroid laboratory tests may be falsified for as long as two years after lymphography.