Leuco-Plus Caution For Usage

Preparation: 1. Leave Leuco-Plus 300 (Vial/Prefilled Syringe) from the refrigerator to allow the solution to reach room temperature before administration.
2. Inspected visually for particulate matter and discoloration prior to administration. Do not use if discoloration is present. Discard any unused solution.
3. Do not shake. Vigorous shaking may denature the glycoprotein and render it biologically inactive.
4. Leuco-Plus 300 (Vial/Prefilled Syringe) is used for subcutaneous injection or Intravenous Infusion administration.
5. If required, Leuco-Plus 300 (Vial/Prefilled Syringe) may be diluted in 5% dextrose. Leuco-Plus 300 diluted to concentrations between 5 and 15 μg/ml should be protected from adsorption to plastic materials by the addition of Albumin (Human) to a final concentration of 2 mg/ml. When diluted in 5% dextrose or 5% dextrose plus Albumin (Human), Leuco-Plus 300 compatible with glass and plastic bottles and materials.
6. Dilution of Leuco-Plus 300 (Vial/Prefilled Syringe) to a final concentration of less than 5 μg/ml is not recommended at any time.
7. Do not dilute with saline solutions at any time; product may precipitate.
8. Leuco-Plus 300 (Vial), using aseptic technics, attach a sterile needle to a sterile syringe. Remove the flip off from the vial containing Leuco-Plus, and wipe the rubber stopper with disinfactant. Insert the needle into the vial, and withdraw into the syringe with an appropriated volume of solution.