Special care should be exercised when Lercadip is used in patient with sick sinus syndrome (if pacemaker is not in situ). Although hemodynamic controlled studies reveal no impairment of ventricular function, care is also required in patients with moderate to severe left ventricular dysfunction. It has been suggested that some short-acting dihydropyridines may be associated with increased cardiovascular risk in patients with ischemic heart disease.
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