Lefloxin Dosage/Direction for Use

LEFLOXIN Intravenous (IV) infusion: Lefloxin IV should only be administered by intravenous infusion.
The dosage depends on the type and severity of the infection and the sensitivity of the causative pathogen.
As with antibiotic therapy in general, administration of Lefloxin IV should be continued for a minimum of 2 to 3 days after the patient has become afebrile or evidence of bacterial eradication has been obtained. (It is usually possible to switch from initial intravenous treatment to the oral route.)
Lefloxin injection should be slowly infused IV, 60 or 90 minutes every 24 hours, over a period of at least 60 minutes for the 250 mg or 500 mg dose or 90 minutes for the 750 mg dose.
The treatment doses are described in the table as follows. (See Tables 1 and 2.)

Click on icon to see table/diagram/image


Click on icon to see table/diagram/image

LEFLOXIN TABLET: Continuously taking the drug until finish the course or as doctor's prescription.
Adults: Administer 100 mg 2-3 times daily, and increased if necessary, 200 mg 3 times daily or as doctor's order.
For specific indications, dosage are in the table as follows. (See Tables 3 and 4.)

Click on icon to see table/diagram/image


Click on icon to see table/diagram/image

Hepatic impairment: Adjustment of Levofloxacin dosage in patients with hepatic insufficiency is not expected to be necessary because Levofloxacin is mainly excreted by kidney.
Pediatric use: Safety of the drug have not been established for any other indication in this age group, the drug must not be used in pediatric patients.
Geriatric use: Dosage of Levofloxacin should be selected carefully because Levofloxacin is substantially eliminated by the kidneys. If geriatric patients have decreased renal function, dosage adjusted as needed based on renal function.