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Signs and Symptoms: Insulin overdosage may lead to severe and sometimes prolonged and life-threatening hypoglycaemia.
Management: Mild episodes of hypoglycaemia can usually be treated with oral carbohydrates. Adjustments in dosage, meal patterns or physical activity may be necessary. More severe episodes with coma, seizure or neurologic impairment may be treated with glucagon (intramuscular or subcutaneous) or concentrated glucose solution (intravenous). Sustained carbohydrate intake and observation may be necessary because hypoglycaemia may recur after apparent clinical recovery.
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