Justima Drug Interactions

Some medicines may stop the Pill from working properly. These include medicines used for the treatment of epilepsy (e.g. primidone, phenytoin, barbiturates, carbamazepine, oxcarbazepine, topiramate, felbamate); tuberculosis (e.g. rifampicin, rifabutin) and the infections (e.g. ritonavir, nevirapine); antibiotics (e.g. penicillins, tetracyclines, griseofulvin) for some other infectious diseases; and the herbal remedy St. John's wort (primarily used for the treatment of depressive moods). Some medicines (e.g. ketoconazole, erythromycin, cyclosporine) may inhibit the metabolism of Justima.
The Pill may also interfere with the working of other medicines. Accordingly, plasma and tissue concentrations may either increase (e.g. cyclosporine) or decrease (e.g. lamotrigine).
There is a theoretical potential for an increase in serum potassium if the patient is taking Justima with other drugs that may increase serum potassium levels. Such drugs include angiotensin-II-receptor antagonists. However in studies in women taking drospirenone (combined with estradiol) together with an ACE inhibitor or indomethacin no significant difference in the potassium blood level could be observed.
Please inform the physician or pharmacist if the patient is taking or have recently taken any other medicines or herbal products, even those not prescribed. Also tell any other physician or dentist who prescribes another medicine (or the dispensing pharmacist) that the patient use Justima. They can tell if there is need to take additional contraceptive precautions and if so, for how long.
Certain laboratory tests may be affected by oral contraceptives.