Jardiance Indications/Uses

JARDIANCE (empagliflozin) tablets are indicated as an adjunct to diet and exercise to improve glycaemic control in adults and pediatric patients aged 10 years and older with type 2 diabetes mellitus.
JARDIANCE (empagliflozin) tablets are indicated to reduce the risk of cardiovascular death in adult patients with type 2 diabetes mellitus and established cardiovascular disease.
JARDIANCE (empagliflozin) tablets are indicated to reduce the risk of cardiovascular death and hospitalization for heart failure in adults with heart failure.
JARDIANCE (empagliflozin) tablets are indicated to reduce the risk of sustained decline in eGFR, end-stage kidney disease, cardiovascular death, and hospitalization in adults with chronic kidney disease at risk of progression.
Limitation of Use: JARDIANCE is not recommended in patients with type 1 diabetes mellitus. It may increase the risk of diabetic ketoacidosis in these patients (see Precautions).
JARDIANCE is not recommended for use to improve glycemic control in patients with type 2 diabetes mellitus with an eGFR less than 30 mL/min/1.73 m². JARDIANCE is likely to be ineffective in this setting based upon its mechanism of action.
JARDIANCE is not recommended for the treatment of chronic kidney disease in patients with polycystic kidney disease or patients requiring or with a recent history of intravenous immunosuppressive therapy or greater than 45 mg of prednisone or equivalent for kidney disease [see Pharmacology: Clinical Trials under Actions]. JARDIANCE is not expected to be effective in these populations.