Pregnancy: Animal studies have shown no adverse effects on the foetus. Isosorbide-5-mononitrate was fetotoxic at maternally toxic doses in the rat. Available evidence is inconclusive or inadequate for determining fetal risk when used in pregnant women. Isosorbide-5-mononitrate should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
Lactation: It is not known if Isosorbide-5-mononitrate is excreted in breast milk. Caution be exercised when administering Isosorbide-5-mononitrate to breast-feeding women. Isosorbide-5-mononitrate should be used during lactation only if the potential benefit justifies the potential risk to the infant.
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