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Angiotensin converting enzyme inhibitors (such as captopril, enalapril, lisinopril, fosinopril, perindopril, ramipril) are known to induce angioedema. This risk could be increased in presence of racecadotril.
In humans, the concomitant treatment with racecadotril and loperamide or nifuroxazide does not modify the kinetics of racecadotril.
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