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Lurasidone is contraindicated in any patient with a known hypersensitivity to lurasidone HCI or any components in the formulation.
Lurasidone is contraindicated with strong CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin, ritonavir, voriconazole, mibefradil, etc.) and strong CYP3A4 inducers (e.g., rifampin, avasimibe, St. John's wort, phenytoin, carbamazepine, etc.).
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