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General precautions: To those patients who are suspected of having an acute, sub or epidural hematoma the drug should be administered only after an adequate treatment of the source of bleeding and upon confirming that there is no hazard of re-bleeding (since otherwise a fall of intracranial pressure is likely to result in re-bleeding).
Since the drug contains sodium chloride, ample caution should be exercised in prescribing it for those patients in whom restriction of salt intake is indicated.
Care must be taken in administering the drug to patients with the following disorders: Impairment of cardiovascular function; Renal disorder; Diabetes insipidus; Diabetes mellitus (Hyperosmolar nonketotic coma may occur).
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