Each mL contains Gemcitabine Hydrochloride USP equivalent to Gemcitabine base 38 mg.
Gemcitabine HCl is a nucleoside metabolic inhibitor that exhibits antitumor activity. Gemcitabine HCl is a white to off-white solid. It is soluble in water, slightly soluble in methanol, and practically insoluble in alcohol and in polar organic solvents.
The chemical name for gemcitabine HCl is 2'-deoxy-2', 2'-difluorocytidine monohydrochloride (β-isomer). The empirical formula for gemcitabine HCl is C9H11F2N3O4·HCl. It has a molecular weight of 299.66. The formulation is supplied in a sterile form for intravenous use only. Vials contain either 200 mg, 1 g, 1.4 g and 2.0 g of gemcitabine HCl (expressed as free base) as a sterile solution.
Excipients/Inactive Ingredients: Also contains Propylene Glycol, Polyethylene Glycol 400, Hydrochloric acid, Sodium hydroxide and Water for Injection.
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