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Retreatment: Do not use more than a single dose to treat a single episode of acute cystitis; repeated daily doses do not enhance efficacy and increase incidence of adverse events.
Selection and use of anti-infectives: Obtain urine specimens for culture and in vitro susceptibility testing before and after completion of therapy.
To reduce development of drug-resistant bacteria and maintain and maintain effectiveness of fosfomycin and other antibacterials, use only for treatment of infections proven or strongly suspected to be caused by susceptible bacteria.
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