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Symptoms: Symptoms include gastrointestinal complaints (nausea, vomiting and diarrhoea), somnolence and dizziness. Cardiac events (tachycardia, bradycardia, hypotension), liver function disturbances, convulsions and coma have also been reported. Fluvoxamine has a wide margin of safety in overdose. Since market introduction, reports of death attributed to overdosage of Faverin alone have been extremely rare. The highest documented dose of Faverin ingested by a patient is 12 grams. This patient recovered completely.
Occasionally, more serious complications were observed in cases of deliberate overdosage of Faverin in combination with other drugs.
Treatment: There is no specific antidote to Faverin. In case of overdose, the stomach should be emptied as soon as possible after tablet ingestion and symptomatic treatment should be given. The repeated use of medicinal charcoal, if necessary accompanied by an osmotic laxative, is also recommended. Forced diuresis or dialysis is unlikely to be of benefit.
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