Exelfos: Side Effects & Dosing

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Special Precautions Use In Pregnancy & Lactation Adverse Reactions Drug Interactions Caution For Usage Storage MIMS Class ATC Classification Thai FDA Category Presentation/Packing

Concise Prescribing Info

Contents

Fosfomycin

Indications/Uses

Susceptible infections eg, acute bacterial cystitis & urethra-vesical syndrome, acute episodes of relapsing bacterial cystitis, nonspecific bacterial urethritis. E. coli. Asymptomatic bacteriuria in pregnancy.

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Dosage/Direction for Use

Women & female adolescent >12 yr Acute uncomplicated cystitis 1 sachet once daily. Prophylaxis for peri-op transrectal prostate biopsy 1 sachet 3 hr prior to procedure & 1 sachet 24 hr after the procedure.

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Overdosage

View Exelfos overdosage for action to be taken in the event of an overdose.

Administration

Should be taken on an empty stomach: Dissolve in a glass of water & take immediately. For acute uncomplicated cystitis in women & female adolescents it should be taken on an empty stomach preferably before bedtime & after emptying the bladder. Take 2-3 hr before or after a meal.

Contraindications

Hypersensitivity. Patients w/ renal impairment (CrCl <10 mL/min).

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Special Precautions

Not to be used in patients w/ fructose intolerance, glucose-galactose malabsorption or sucrase-isomaltase insufficiency. Persistent infection & male patients w/ UTI. Should only be used during pregnancy if clearly necessary. Single dose of oral fosfomycin can be used during breast-feeding. Childn <12 yr.

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Use In Pregnancy & Lactation

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Adverse Reactions

Vulvovaginitis; headache, dizziness; diarrhea, nausea, dyspepsia, abdominal pain.

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Drug Interactions

Reduced oral absorption w/ metoclopramide. Absorption may be delayed w/ food. Increased anticoagulant activity in patients receiving antibiotics therapy eg, fluoroquinolones, macrolides, cyclins, clotrimozaxole & certain cephalosporins.

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Caution For Usage

For caution against possible variation of physical aspect of medicine... Click to view Exelfos detailed prescribing information

Storage

View Exelfos storage conditions for details to ensure optimal shelf-life.

Description

View Exelfos description for details of the chemical structure and excipients (inactive components).

Action

View Exelfos mechanism of action for pharmacodynamics and pharmacokinetics details.

MIMS Class

Other Antibiotics

ATC Classification

J01XX01 - fosfomycin ; Belongs to the class of other antibacterials. Used in the systemic treatment of infections.

Thai FDA Category

Presentation/Packing

Form

Exelfos granules for oral soln 3 g

Packing/Price

1's

Exelfos

fosfomycin

Manufacturer:

Exeltis

Distributor:

DKLL

Marketer:

Exeltis