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Epotiv Prefilled lnj. should be cautiously administered to following patients: Patients with hypertension (Rise in blood pressure caused by erythropoietin administration has been recognized and hypertensive encephalopathy may rise).
Patients with history of hypersensitivity to drug.
Patients with predisposition to allergy.
Patients with myocardial infarction, pulmonary infarction, cerebral infarction and so on, on patients with a chance of thromboembolism by the history of these (It has been reported that the blood viscosity increases with erythropoietin and thromboembolism may be exacerbated or induced. Also since there is a chance of acceleration in blood coagulation, especially in case erythropoietin is administered in order to store autologous blood and after operation, sufficient monitoring is required).
Premature with ventricular hemorrhage and intracerebral hemorrhage (Cerebral hemorrhage may be exacerbated by erythropoietin administration).
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