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Encapon 200

Encapon 200

entacapone

Manufacturer:

Unison

Distributor:

Medline

Marketer:

B.Grimm Pharma
Concise Prescribing Info
Contents
Entacapone
Indications/Uses
Adjunct to levodopa/benserazide or levodopa/carbidopa in patients w/ Parkinson's disease.
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Dosage/Direction for Use
Adult 200 mg tab taken w/ each levodopa/dopa-decarboxylase inhibitor dose. Max: 200 mg 10 times daily.
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Overdosage
View Encapon 200 overdosage for action to be taken in the event of an overdose.
Administration
May be taken with or without food.
Contraindications
Hypersensitivity. Pheochromocytoma. History of NMS &/or non-traumatic rhabdomyolysis. Concomitant use w/ non-selective MAOI, selective monoamine oxidase (MAO)-A inhibitors + MAO-B inhibitors. Hepatic impairment.
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Special Precautions
Orthostatic HTN/syncope, diarrhea/colitis, rhabdomyolysis, falling asleep during activities of daily living w/ or w/o somnolence, NMS, dyskinesia, compulsive behaviors/impaired impulse control. Patients w/ ischemic heart disease. Not recommended in childn <18 yr.
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Adverse Reactions
Nausea, vomiting, urine discoloration, fatigue, increased sweating, fall, diarrhea, abdominal pain, dry mouth, constipation, dyskinesia, insomnia, hallucinations, confusion, nightmares, ischemic heart disease events.
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Drug Interactions
Increased risk for bleeding w/ warfarin. Concomitant use w/ medicinal products metabolized by catechol-O-methyl-transferase (COMT) (eg, rimiterol, isoprenaline, adrenaline, noradrenaline, dopamine, dobutamine, α-methyldopa, apomorphine & paroxetine); chelates w/ Fe; drugs bound w/ human albumin binding site II (eg, diazepam & ibuprofen).
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Action
View Encapon 200 mechanism of action for pharmacodynamics and pharmacokinetics details.
MIMS Class
Antiparkinsonian Drugs
ATC Classification
N04BX02 - entacapone ; Belongs to the class of other dopaminergic agents used in the management of Parkinson's disease.
Presentation/Packing
Form
Encapon 200 tab 200 mg
Packing/Price
1 × 10's;10 × 10's;3 × 10's
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