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These are essentially dose-dependent and can therefore be controlled by reducing the infusion rate. Since dobutamine is almost completely eliminated within 10 min, the side effects will disappear promptly with a reduction of dosage or discontinuation of infusion.
Nausea, headache, palpitation, dyspnea and chest pain have been reported as the most common side effects.
Anginal pain, shortness of breath, skin rash, eosinophilia and bronchospasm.
Increased heart rate, blood pressure and ventricular ectopic activity.
Hypotension: Precipitous decreases in blood pressure have occasionally been described in association with dobutamine therapy.
Reactions at sites of i.v. infusion. Phlebitis occasionally been reported.
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