Dexton Dosage/Direction for Use

Adults Dosing: Intramuscular or intravenous administration: Dose depend upon condition being treated and response of patient and then decrease in small increments at appropriate interval until the lowest dose that maintains a favorable response is reached. (See Table 1.)

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Intra-articular or soft tissue injection: See Table 2.

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Intralesional injection: See Table 3.

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Pediatric Dosing: Corticosteroids cause growth retardation in infancy, childhood and adolescence, which may be irreversible. Treatment should be limited to the minimum dosage for the shortest possible time. In order to minimize suppression of the hypothalamic pituitary-adrenal axis and growth retardation, treatment should be limited, where possible, to a single dose on alternate days.
Growth and development of infants and children on prolonged corticosteroid therapy should be carefully monitored.
Dosage requirements are variable and may have to be changed according to individual need. Usually 0.2 mg/kg-0.4 mg/kg (0.05 mL/kg-0.1 mL/kg) of body weight daily.
Geriatrics dosing: Use cautiously in the elderly in the smallest possible dose.
Dosage in renal impairments: No specific dosage adjustment is necessary, use with caution in renal impairment patients.
Supplemental dose is not necessary in hemodialysis or peritoneal dialysis.
Dosage in hepatic impairments: The effect of baseline hepatic impairment on the pharmacokinetics of the drug has not been studied. Use with caution in patient with hepatic impairment.