Do not prescribe DELSIA to women who are known to have the following: Renal impairment; Adrenal insufficiency; A high risk of arterial or venous thrombotic diseases. Examples include women who are known to: Smoke, if over age 35 years (see PRECAUTIONS); Have deep vein thrombosis or pulmonary embolism, now or in the past (see PRECAUTIONS); Have cerebrovascular disease (see PRECAUTIONS); Have coronary artery disease (see PRECAUTIONS); Have thrombogenic valvular or thrombogenic rhythm diseases of the heart (for example, subacute bacterial endocarditis with valvular disease, or atrial fibrillation) (see PRECAUTIONS); Have inherited or acquired hypercoagulopathies (see PRECAUTIONS); Have uncontrolled hypertension (see PRECAUTIONS); Have diabetes mellitus with vascular disease (see PRECAUTIONS); Have headaches with focal neurological symptoms or have migraine headaches with or without aura if over age 35 years (see PRECAUTIONS).
Undiagnosed abnormal uterine bleeding (see PRECAUTIONS); Breast cancer or other estrogen- or progestin-sensitive cancer, now or in the past (see PRECAUTIONS); Liver tumor (benign or malignant) or liver disease (see PRECAUTIONS); Pregnancy, because there is no reason to use COCs during pregnancy (see PRECAUTIONS and USE IN PREGNANCY & LACTATION); Use of Hepatitis C drug combinations containing ombitasvir/paritaprevir/ritonavir, with or without dasabuvir due to the potential for ALT elevations (see PRECAUTIONS and INTERACTIONS).
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