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Hepatitis was reported in one patient who received 2 to 3 times the prescribed dose of deferasirox over a period of several weeks. In iron overloaded thalassemic patients, single doses up to 80 mg/kg have been tolerated with nausea and diarrhea noted. Single doses up to 40 mg/kg were tolerated in healthy volunteers.
Acute signs of overdose may include nausea, vomiting, headache, and diarrhea. Overdose may be treated by induction of emesis or by gastric lavage and by symptomatic treatment.
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