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Overdose and Treatment: 200 mg: Management of mild to moderate toxicity: Require only supportive care.
Management of severe toxicity: Support respiratory and cardiovascular function as needed. Gastrointestinal hemorrhage is a possibility and can be managed supportively with standard treatment measures.
Dialysis is unlikely to be an efficient method of Celecoxib removal because of high protein binding of the drug.
400 mg: Clinical experience of overdose is limited. Single doses up to 1,200 mg and multiple doses up to 1,200 mg twice daily have been administered to healthy subjects without clinically significant adverse effects. In the event of suspected overdose, appropriate supportive medical care should be provided. Dialysis is unlikely to be an efficient method of drug removal because of high protein binding of the drug.
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