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Use in Pregnancy: Colofac: Only a very limited amount of information on the use of mebeverine in pregnant women is available. Animal studies are insufficient with respect to reproductive toxicity. Do not take Colofac if pregnant.
Colofac Retard: Animal experiments have failed to show any teratogenic effects. However, the usual precautions concerning the administration of any drug during pregnancy should be observed.
Use in Lactation: Colofac: It is unknown whether mebeverine or its metabolites is excreted in human milk. The excretion of mebeverine in milk has not been studied in animals. Do not take Colofac while breastfeeding.
Colofac Retard: Colofac Retard is not excreted in milk of lactating women after therapeutic doses.
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