Cissabex Adverse Reactions

The following convention has been used for the classification of frequency: very common (≥1/10), common (≥1/100 to <1/10), uncommon (≥1/1,000 to <1/100), rare (>1/10,000 to <1/1,000), very rare (<1/10,000).
Clinical trial data: Cardiac disorders: Common: Bradycardia.
Vascular disorders: Common: Hypotension.
Uncommon: Cutaneous flushing.
Respiratory, thoracic and mediastinal disorder: Uncommon: Bronchospasm.
Skin and subcutaneous tissue disorders: Uncommon: Rash.
Post marketing data: Immune system disorders: Very rare: Anaphylactic reaction.
Anaphylactic reaction of varying degrees of severity have been observed after the administration of neuromuscular blocking agents. Very rarely, severe anaphylactic reactions have been reported in patients receiving Cissabex in conjunction with one or more anesthetic agents.
Musculoskeletal and connective tissue disorders: Very rare: Myopathy, muscle weakness.
There have been some reports of muscle weakness and/or myopathy following prolonged use of muscle relaxants in severely ill patients in the ICU. Most patients were receiving concomitant corticosteroids. These events have been reported infrequently in association with Cissabex and a causal relationship has not been established.