Hypersensitivity to tadalafil or any of the excipients of Cialis.
In clinical studies, tadalafil was shown to augment the hypotensive effects of nitrates. This is thought to result from the combined effects of nitrates and tadalafil on the nitric oxide/cGMP pathway. Therefore, administration of tadalafil to patients who are using any form of organic nitrate is contraindicated (see Interactions).
Agents for the treatment of erectile dysfunction, including tadalafil, should not be used in men with cardiac disease for whom sexual activity is inadvisable. Physicians should consider the potential cardiac risk of sexual activity in patients with pre-existing cardiovascular disease.
The following groups of patients with cardiovascular disease were not included in clinical trials and the use of tadalafil is therefore contraindicated: Patients with myocardial infarction within the last 90 days; with unstable angina or angina occurring during sexual intercourse; with New York Heart Association Class ≥2 heart failure in the last 6 months; with uncontrolled arrhythmias, hypotension (<90/50 mmHg) or uncontrolled hypertension; with a stroke within the last 6 months.
Cialis 5 mg: Tadalafil is contraindicated in patients who have loss of vision in one eye because of non-arteritic anterior ischemic optic neuropathy (NAION), regardless of whether this episode was in connection or not with previous PDE5 inhibitor exposure (see Precautions).
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