Adults and children over 11 years of age should receive the contents of one vial per day. 5 ml of Water for injections should first be added by syringe into the vial and gently mixed to dissolve the lyophilized powder. If infused intravenously, Cernevit should be administered slowly. If injected intravenously, the injection must be administered slowly (over at least 10 minutes).
Cernevit may be included in the composition of parenteral nutrition mixtures combining carbohydrates, lipids, amino acids, electrolytes and trace elements, provided that compatibility and stability have been confirmed. The patient's clinical status and vitamin levels should be monitored to ensure maintenance of adequate levels.
It should be taken into account that some vitamins, especially A, B2, and B6 are sensitive to ultraviolet light (e.g., direct or indirect sun light). In addition, loss of vitamins A, B1, C, and E may increase with higher levels of oxygen in the solution. These factors should be considered if adequate vitamin levels are not achieved.
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