Cerebrolysin Dosage/Direction for Use

Single doses of up to 50ml can be administered, but a course of therapy is the preferred option.
A recommended optimum course of therapy comprises daily application over a total of 10-20 days.
Daily recommendations/Daily dose: Organic brain disorders, metabolic disorders and neurodegenerative diseases (dementia): 5-30ml; postapoplectic complications: 10-50ml; craniocerebral trauma 10-50ml; children 1-2ml.
The effectiveness of therapy can be increased by repeated courses, until no further benefit results. After the initial course, the frequency of doses may be reduced to 2 or 3 times per week. A treatment-free period, equal in length to the therapy course, should be allowed between successive therapy courses.
Doses of up to 5ml IM and up to 10ml undiluted IV may be given. Doses between 10ml up to a maximum of 50ml are recommended only as a slow intravenous infusion after dilution with the suggested standard infusion solutions. The duration of the infusion should be between 15 and 60 mins.
The compatibility over 24 hours at room temperature in the presence of light has been tested with the following standard infusion solutions: 0.9% sodium chloride solution (9mg NaCl/ml); Ringer's solution (Na⁺153.98mmol/l, Ca²⁺2.74mmol/l, K⁺4.02mmol/l, Cl^-163.48mmol/l); 5% Glucose.
Vitamins and cardiovascular drugs may be given concomitantly with Cerebrolysin but the drugs should not be mixed with Cerebrolysin in the syringe.