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Coadministration of Terfenadine or Astemizole with CANDITRAL is also contraindicated in patients with known hypersensitivity to the drug. Caution should be used in prescribing CANDITRAL to patients with hypersensitivity to other azoles.
CANDITRAL is contraindicated in pregnancy and appropriate means of contraception should be employed in women of childbearing potential. CANDITRAL is excreted in human milk and should no be administered to nursing mothers.
The efficacy and safety of CANDITRAL have not been established in children. A small number of patients between 3-16 years of age have been treated with 100 mg/day of CANDITRAL for systemic fungal infections and no serious adverse effects have been reported.
CANDITRAL should not be used in patients taking Rifampicin which appears to initially inhibit and then enhance metabolism of Itraconazole.
Use of CANDITRAL in patients with non-life threatening conditions who have known hepatic disease is not advised.
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