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Suppression of lactation
Adult: For the suppression of lactation for medical reasons: Initially, 2.5 mg daily for 2-3 days, then increase to 2.5 mg bid for 14 days. Treatment recommendations may vary among countries and individual products (refer to specific product guidelines).
Oral
Acromegaly
Adult: As an adjunct to surgery and/or radiotherapy to reduce circulating growth hormone: Initially, 1-1.25 mg given at night, then increased to 2-2.5 mg after 2-3 days. May be subsequently increased by 1 mg at 2-3 day intervals, until a dose of 2.5 mg bid is achieved. Doses may be further increased by 2.5 mg daily at 2-3 day intervals in the following scheme: 2.5 mg 8 hourly, 2.5 mg 6 hourly, then 5 mg 6 hourly. Dosage and treatment recommendations may vary among countries and individual products (refer to specific product guidelines).
Oral
Hyperprolactinaemia
Adult: For the treatment of disorders associated with hyperprolactinaemia (e.g. amenorrhoea with or without galactorrhoea, hypogonadism, or infertility): Initially, 1-1.25 mg given at night, then increased to 2-2.5 mg after 2-3 days. May be subsequently increased by 1 mg at 2-3 day intervals, until a dose of 2.5 mg bid is achieved. Usual dose: 7.5 mg daily in divided doses, increased up to 30 mg daily as necessary. In cases of infertility without hyperprolactinaemia, the usual dose is 2.5 mg bid. Dosage recommendations may vary among countries and individual products (refer to specific product guidelines).
Child: ≥7 years Doses are initiated and adjusted according to growth hormone levels. Max daily dose: 7-12 years 10 mg; 13-17 years 20 mg. Dosage recommendations may vary among countries and individual products (refer to specific product guidelines).
Child: ≥7 years Doses are initiated and adjusted according to growth hormone levels. Max daily dose: 7-12 years 10 mg; 13-17 years 20 mg. Dosage recommendations may vary among countries and individual products (refer to specific product guidelines).
Oral
Parkinson's disease
Adult: As adjunct to levodopa: Week 1: 1-1.25 mg at bedtime; Week 2: 2-2.5 mg at bedtime; Week 3: 2.5 mg bid; Week 4: 2.5 mg tid. Doses may be increased by 2.5 mg every 3-14 days according to patient's response, adjusted until the optimum dose is achieved. Maintenance dose: 10-30 mg daily. Max: 30 mg daily. Dosage recommendations may vary among countries and individual products (refer to specific product guidelines).
Oral
Prolactinoma (prolactin secreting adenoma)
Adult: To reduce tumour size, particularly in patients at risk of optic nerve compression: Initially, 1-1.25 mg given at night, then increased to 2-2.5 mg after 2-3 days. May be subsequently increased by 1 mg at 2-3 day intervals, until a dose of 2.5 mg bid is achieved. Doses may be further increased by 2.5 mg daily at 2-3 day intervals in the following scheme: 2.5 mg 8 hourly, 2.5 mg 6 hourly, then 5 mg 6 hourly. Max: 30 mg daily. Dosage and treatment recommendations may vary among countries and individual products (refer to specific product guidelines).
Child: ≥7 years 1 mg bid or tid, gradually increase dose to several tabs daily as needed to suppress the plasma prolactin levels adequately. Max daily dose: 7-12 years 5 mg; 13-17 years 20 mg. Dosage recommendations may vary among countries and individual products (refer to specific product guidelines).
Child: ≥7 years 1 mg bid or tid, gradually increase dose to several tabs daily as needed to suppress the plasma prolactin levels adequately. Max daily dose: 7-12 years 5 mg; 13-17 years 20 mg. Dosage recommendations may vary among countries and individual products (refer to specific product guidelines).
Oral
Prophylaxis of puerperal lactation
Adult: 2.5 mg on the day of delivery, then 2.5 mg bid for 14 days. Initiate treatment within a few hours of parturition once vital signs have been stabilised. Treatment recommendations may vary among countries and individual products (refer to specific product guidelines).
Oral
Diabetes mellitus
Adult: Cycloset As an adjunct to diet and exercise to improve glycaemic control: Initially, 0.8 mg once daily in the morning. If additional glycaemic control is needed, doses may be increased by 0.8 mg at weekly intervals as tolerated. Maintenance dose: 1.6-4.8 mg once daily. Max: 4.8 mg daily. Treatment recommendations may vary among countries and individual products (refer to specific product guidelines).
