Biolet Overdosage

Symptoms: Bradycardia, hypotension, low-output cardiac failure, and cardiogenic shock are the most common effects of beta-blocker intoxication.
Cardiovascular: Asystole, tachycardia (partial agonist), prolonged QT interval (sotalol), prolonged QRS complex (membrane-stabilizing agents), ventricular dysrhythmias (membrane-stabilizing agents, sotalol), hypotension, hypertension (partial agonist); bradycardia, AV block.
Central nervous system: Seizures; coma; depressed level of consciousness.
Gastrointestinal: Mesenteric ischemia; esophageal spasms.
Metabolic: Hyperkalemia; hypoglycemia.
Respiratory: Apnea; cyanosis; respiratory depression; bronchospasm.
Miscellaneous: Renal failure.
Treatment: Perform evaluation of the "ABCs" (airway, breathing, and circulation) as well as rapid assessment of serum glucose levels with correction of hypoglycemia using IV glucagon. Early ventilatory control is essential in addition to chest radiography, serum electrolytes, and arterial blood gases. Administer activated charcoal to all patients and perform gastric lavage in patients who present within 1 to 2 hours after ingestion.