Pharmacology: Pharmacodynamics: Histamine antagonist with selective peripheral H1 receptor antagonist affinity and no affinity for muscarinic receptors.
Pharmacokinetics: Onset of action: 1 hour.
Duration: 26 hours.
Absorption: Rapid.
Protein binding: 84% to 90%.
Metabolism: Minimal (~5% of dose).
Bioavailability: ~61%.
Half-life elimination: ~14.5 hours.
Time to peak: 1.13 hours.
Excretion: Feces (67%, as unchanged bilastine); Urine (28%, as unchanged bilastine).
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