BEtt Adverse Reactions

Local reactions, such as pain, erythema, induration, and tenderness, are common after the administration of Tetanus Toxoid. Such local reactions are usually self limited and require no therapy. Nodule, sterile abscess formation, or subcutaneous atrophy may occur at the site of injection. Systemic reactions, such as fever, chills, myalgias, and headaches, also may occur. Arthus type hypersensitivity reactions, or high fever, may occur in persons who have very high serum antitoxin antibodies due to frequent injections of toxoid.
Neurological complications such as convulsions, encephalopathy, and various mono and polyneuropathies, including guillain-barre syndrome, have been reported following administration of preparations containing tetanus antigen.
Urticaria, erythema multiforme or other rash, arthralgias, and more rarely, a severe anaphylactic reaction (i.e., urticaria with swelling of the mouth, difficulty in breathing, hypotension, or shock) have been reported following administration of preparations containing tetanus antigen.