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Pregnancy: Pregnancy category: B.
Adverse events were not observed in animal reproduction studies. Azithromycin crosses the placenta. Fetal malformations have not been observed following maternal use of azithromycin. The maternal serum half-life of azithromycin is unchanged in early pregnancy and decreased at term; however, high concentrations of azithromycin are sustained in the myometrium and adipose tissue.
There are no adequate and controlled studies to date using azithromycin in pregnant women, and the drug should be used during pregnancy only when clearly needed.
Lactation: Azithromycin has been detected in human milk. The drug should be used with caution in nursing women.
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