Azith Dosage/Direction for Use

Recommended dose: Dosing of therapy depends on the severity of the infection, patient's condition and susceptibility of organisms or to be used as directed by the physician.
The drug should be taken in complete treatment course or as directed by the physician.
Oral Azithromycin should be administered as a single daily dose. Each dose should be taken at least 1 hour before meal or 2 hours after meal.
In adults: For the treatment of adult patients with CAP due to the indicated organisms, the recommended dose of IV Azithromycin is 500 mg as a single daily dose for at least 2 days. IV therapy should be followed by AZITH (250 MG CAPSULE) at a single daily dose of 500 mg to complete a 7- to 10-day course of therapy. The timing of the conversion to oral therapy should be done at the discretion of the physician and in accordance with clinical response.
For the treatment of adult patients with PID due to the indicated organisms, the recommended dose of IV Azithromycin is 500 mg as a single daily dose by the IV route for 1 or 2 days. IV therapy should be followed by AZITH (250 MG CAPSULE) at a single daily dose of 250 mg to complete a 7-day course of therapy. The timing of the conversion to oral therapy should be done at the discretion of the physician and in accordance with clinical response. If anaerobic microorganisms are suspected of contributing to the infection, an antimicrobial agent with anaerobic activity may be administered in combination with Azithromycin.
For the treatment of sexually transmitted diseases caused by Chlamydia trachomatis and Haemophilus ducreyi, the dose is 1000 mg as a single oral dose. For susceptible Neisseria gonorrhoeae, the recommended dose is 1000 mg or 2000 mg of Azithromycin orally in combination with 250 mg or 500 mg of Ceftriaxone according to local clinical treatment guidelines. For patients who are allergic to penicillin and/or cephalosporins, prescribers should consult local treatment guidelines.
For prophylaxis against MAC infections in patients infected with the HIV, the dose is 1200 mg orally once per week.
For the treatment of DMAC infections in patients with advanced HIV infection, the recommended dose is 600 mg orally once a day. Azithromycin should be administered in combination with ethambutol at the approved dose.
For all other indications in which the oral formulation is administered, the total dosage of 1500 mg should be given as 500 mg daily for 3 days. As an alternative, the same total dose can be given over 5 days with 500 mg given on day 1, then 250 mg daily on days 2 to 5.
Mode of administration: Administration of AZITH (ORAL SUSPENSION 200 MG/5 ML): Tap the bottle to loosen the powder. Pull the measuring cup out to measure the volume of 9 mL as specified. Then open the bottle cap to fill water in a bottle containing medicinal powder. Close the bottle cap, shake to wet and disperse the powder. Finally, AZITH (ORAL SUSPENSION 200 MG/5 ML) (1 teaspoon) will be obtained as directed in the label.
Shake well before used. Shake prior to use everytime.
For children weighing less than 15 kg, the suspension should be measured as closely as possible. For children weighing 15 kg or more, the suspension should be administered using an appropriate measuring spoon.
The reconstituted product can be kept for 10 days below 30°C.
In Children: AZITH (250 MG CAPSULE) should be only administered to children weighing more than 45 kg.
The maximum recommended total dose for any treatment is 1500 mg for children.
Total dose of 30 mg/kg should be given as a single daily dose of 10 mg/kg daily for 3 days, or given over 5days with a single daily dose of 10 mg/kg on Day 1, then 5 mg/kg on Days 2-5.
AZITH (ORAL SUSPENSION 200 MG/5 ML) should be administered orally according to the guide provided as follows: See table.

Click on icon to see table/diagram/image

For pediatric streptococcal pharyngitis (only in patients who are contraindicated with penicillin, which is the first choice treatment), Azithromycin given as a single dose of 10 mg/kg or 20 mg/kg orally for 3 days has been shown to be effective. However, a daily dose of 500 mg must not be exceeded.
Treatment for children with acute otitis media, can be given as a single recommended dose of 30 mg/kg orally.
The safety and efficacy of IV Azithromycin for the treatment of infections in children have not been established.
In the elderly: The same dosage as in adult patients is used in the elderly.
In patients with renal impairment: No dosage adjustment is necessary in patients with mild to moderate renal impairment (GFR 10-80 mL/min). Caution should be exercised when Azithromycin is administered to patients with severe renal impairment (GFR < 10 mL/min).
In patients with hepatic impairment: The same dosage as in patients with normal hepatic function may be used in patients with mild to moderate hepatic impairment.