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Labetalol hydrochloride injection is contraindicated in bronchial asthma, overt cardiac failure, greater than first degree heart block, cardiogenic shock, severe bradycardia (<45-50 bpm), other conditions associated with severe and prolonged hypotension, and in patients with a history of hypersensitivity to any component of the product. Beta-blockers, even those with apparent cardio-selectivity, should not be used in patients with a history of obstructive airway disease, including asthma.
When peripheral vasoconstriction suggests low cardiac output, the use of labetalol hydrochloride injection control hypertensive episodes following acute myocardial infarction is contraindicated.
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