Atorvin Warnings

Based on the notification of the Ministry of Public Health: Do not use the drug in pregnant and breast-feeding women.
Do not use the drug in patients with liver disease.
If there is myalgia at calf, back or whole body, stop taking drug and consult physician.
Liver function tests should be performed before taking drug 6 and 12 weeks after taking drug. For patients who routinely use the drug, liver function tests should be performed every 6 months or as recommended by a physician. If the transaminase level is greater than three times of upper normal limit, stop taking drug and consult physician.
Use with caution with digoxin, warfarin because the level of these drugs in blood may be high and become dangerous.
The risk of myopathy of rhabdomyolysis will increase when administer the drug with other following drugs, e.g., azole antifungal such as ketoconazole, itraconazole, macrolides such as erythromycin, clarithromycin; HIV protease inhibitors such as indinavir, ritonavir, nelfinavir, saquinavir; verapamil, diltiazem, gemfibrozil, nicotinic acid, cyclosporine, amiodarone.
The risk of rhabdomyolysis will increase under the following conditions, e.g., use at high dose, the elderly; patients with hepatic or renal insufficiency, alcoholism, patients with hypothyroidism.
Caution should be exercised when taking this drug with colchicine especially in the elderly or patients with renal insufficiency because there is a risk of myopathy or rhabdomyolysis.
The use of this drug may increase the risk of increasing in blood sugar level.