Advertisement
Advertisement
Apolets

Apolets Description

clopidogrel

Manufacturer:

Apotex

Distributor:

Berlin Pharm
Full Prescribing Info
Description
Each film-coated tablet contains Clopidogrel bisulfate 98.0 mg equivalent to 75 mg of clopidogrel base.
Clopidogrel bisulfate is an inhibitor of ADP-induced platelet aggregation acting by direct inhibition of adenosine diphosphate (ADP) binding to its receptor and of the subsequent ADP-mediated activation of the glycoprotein GPIIb/IIIa complex. Chemically it is Methyl (+)-(S)-a-(o-chlorophenyl)-6,7-dihydrothieno[3,2-c]pyridine-5(4H)-acetate,sulfate (1:1). The empirical formula of clopidogrel bisulfate is C16H16ClNO2S·H2SO4 and its molecular weight is 419.90.
Clopidogrel bisulfate is a white to off-white powder. It is practically insoluble in water at neutral pH but freely soluble at pH 1. It also dissolves freely in methanol, dissolves sparingly in methylene chloride, and is practically insoluble in ethyl ether. It has a specific optical rotation of about +56°.
Excipients/Inactive Ingredients: Each tablet contains  anhydrous lactose, colloidal silicon dioxide, crospovidone, methylcellulose and zinc stearate. The reddish brown film coating contains ferric oxide, hydroxypropyl cellulose, hypromellose 2910 E5, polyethylene glycol 8000 and titanium dioxide.
Advertisement
Advertisement
Advertisement
Advertisement
Advertisement
Advertisement