Adult HTN Initially 5 mg once daily w/o concurrent diuretic or 2.5 mg once daily on existing diuretic. Maintenance: 10-40 mg once daily or in 2 divided doses.
Symptomatic heart failure Initially 2.5 mg once daily or bid. Maintenance: 2.5-20 mg bid. Max: 40 mg daily in divided doses.
Asymptomatic left ventricular dysfunction & MI Initially 2.5 mg bid. Maintenance: 2.5-10 mg bid. Max: 20 mg daily in divided doses.
Patients w/ kidney disease (diabetic & non-diabetic) Initially 5 mg daily. Maintenance: 5-20 mg daily. Max: 20 mg daily.
Patients w/ impaired renal function, moderate to severe impairment (CrCl ≤30 mL/min) Initially 2.5 mg daily. Max: 40 mg daily.
Childn (6 mth-16 yr) HTN Initially 0.08 mg/kg (max: 5 mg) once daily. Maintenance: 0.08-0.58 mg/kg daily. Max: 0.58 mg/kg (40 mg) daily.
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